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Open Journal of Analytical and Bioanalytical Chemistry

    Abstract

    Open Access Research Article Article ID: OJABC-3-114

    Development and validation of stability indicating RP-HPLC method for simultaneous estimation of Ibuprofen and Carisoprodol in Pharmaceutical formulation

    A Lakshmana Rao* and P Vijetha

    A novel, rapid, precise and accurate stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Ibuprofen and Carisoprodol in combined pharmaceutical formulation. Chromatographic separation was achieved on Kromasil C18 column (250×4.6mm, 5μm) with UV detection at 260nm. The mobile phase consisting of 0.1% Ortho Phosphoric Acid (OPA) and acetonitrile in a ratio of 40:60v/v and adjusted the fl ow of mobile phase to 1.0mL/min.

    Keywords:

    Published on: Nov 6, 2019 Pages: 72-75

    Full Text PDF Full Text HTML DOI: 10.17352/ojabc.000014
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    Tsuyoshi Shirakawa
    Kyushu University, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
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    Prof. Pierre Guertin
    Laval University, Canada
    International Journal of Pharmaceutical Sciences and Developmental Research
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    University of Athens, Greece
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    Malgorzata Gabriela WASNIEWSKA
    University of Messina, Italy
    International Journal of Clinical Endocrinology and Metabolism
    Dr. Pierre Guertin
    Laval University, Canada
    Archive of Gerontology and Geriatrics Research
    Massimiliano VISOCCHI 
    Catholic University of Rome, Italy
    Open Journal of Orthopedics and Rheumatology
    M.Waheed Roomi
    Dr. Rath Research Institute
    1260 Memorex Drive, Santa Clara, USA
    Global Journal of Cancer Therapy
    Francesco Marotta
    ReGenera R&D International for Aging Intervention & San Babila Clinic, Milano, Italy
    Archives of Clinical Gastroenterology
    Giuseppe Murdaca
    University of Genoa, Italy
    Global Journal of Allergy
    Dong Zhao
    China University of Political Science and Law, China
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